The past decade has brought great advances in our understanding of
the mechanisms underlying auditory pathologies. Molecular biology
and genetics have primarily contributed to this enhanced
understanding, which in turn has driven the design of novel
rational therapeutic interventions. Auditory Trauma, Protection and
Repair presents recent developments in auditory research and their
potential translation to the clinical setting. In particular the
authors address the major entities of peripheral auditory trauma,
discuss the underlying mechanisms, the central nervous system
consequences, protective interventions and finally explore the
possibilities to restore cochlear morphology and function.
Two themes run through the chapters in this book: cellular
homeostasis and cell death. In the broadest sense, all auditory
pathologies are disorders of cellular homeostasis.
Contents:
- Auditory Pathology: When Hearing Is Out of Balance Jochen
Schacht
- Genetics of Hearing Loss Ella Shalit and Karen B. Avraham
- Cochlear Homeostasis and Homeostatic Disorders Philine
Wangemann
- Tinnitus: Theories, Mechanisms and Treatments Carol A. Bauer
and Thomas J. Brozoski
- Autoimmune Inner Ear Disease Quinton Gopen, and Jeffrey P.
Harris
- Age-Related Hearing loss and Its Cellular and Molecular Bases
Kevin K. Ohlemiller and Robert D. Frisina
- The Patterns and Mechanisms of Noise-Induced Cochlear Pathology
Donald Henderson, Bohua Hu, and Eric Bielefeld
- Drug-Induced Hearing Loss Leonard P. Rybak, Andrea E. Talaska,
and Jochen Schacht
- Central Consequences ofCochlear Trauma D. Kent Morest and
Steven J. Potashner
- Cell Death and Cochlear Protection Steven Green, Richard A.
Altschuler, and Josef M. Miller
- Emerging Strategies for Restoring the Cochlea Stefan Heller and
Yehoash Raphael
About the editors:
Jochen Schacht is Professor and Director of the Kresge Hearing
Research Institute, University of Michigan, Ann Arbor. Arthur N.
Popper is Professor in the Department of Biology and Co-Director of
the Center for Comparative and Evolutionary Biology of Hearing at
the University of Maryland, College Park. Richard R. Fay is
Director of the Parmly Hearing Institute and Professor of
Psychology at Loyola University of Chicago.
About the series:
The Springer Handbook of Auditory Research presents a series of
synthetic reviews of fundamental topics dealing with auditory
systems. Each volume is independent and authoritative; taken as a
set, this series is the definitive resource in the field.
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