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Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Neurosciences
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Cyclic Nucleotides in the Nervous System (Paperback, Softcover reprint of the original 1st ed. 1977)
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Cyclic Nucleotides in the Nervous System (Paperback, Softcover reprint of the original 1st ed. 1977)
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The elucidation of the cellular and molecular bases underlying the
inte grated function of the central nervous system, both in disease
and in health, must ultimately come from the combined efforts of
scientists from many disciplines, including biology, chemistry,
histology, pathology, physiology, pharmacology, and psychology.
Communication between scientists from these various
disciplines-vital to the advancement of our understanding of the
function of the nervous system-has become more and more difficult
in recent years. Both increasing specialization and the incredible
increases in publications pertinent to brain research in a wide
spectrum of journals, in symposium volumes, in monographs, in
abstracts, and in reviews contrib ute to the problems of
cross-communication and even of communication within a scientific
discipline. Research on the significance of cyclic nucleo tides to
the function of nervous systems is particularly illustrative of the
communication problem. Since the initial publications by
Sutherland, Rall, and Butcher in the late fifties and early sixties
on high levels of adenylate cyclase, phosphodiesterases, and cyclic
AMP in brain, the ensuing litera ture of this field has expanded
exponentially. At the present time, from five to ten publications
relevant to cyclic nucleotides and the nervous system appear each
week. Indeed, these are minimal numbers based mainly on examination
of literature titles and key index words. Many articles concerned
with some aspect of central function contain, buried within their
text, experiments with or related to cyclic nucleotides."
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