When the fourth edition of The Guide to Living with HIV Infection
was published in 1998, the effects of the new drugs against HIV
were only beginning to be appreciated. Since that time, rates of
hospitalization, serious illness, and death have dropped by 60 to
80 percent and have stayed down. Several years ago, one young woman
with no remaining immune system had made the decision, despite her
odds, to be kept alive artificially; she now lives a healthy life,
has a near-normal immune system, and, for the last three years, has
had no detectable HIV. Her world, and the world for most people
affected by HIV infection, is radically changed.
In this new edition of their acclaimed guide, Dr. John Bartlett,
director of the Infectious Diseases Division at the Johns Hopkins
Hospital, and science writer Ann Finkbeiner thoroughly update their
discussion of the disease, from the evolving issue of when to start
treatment to the new and sophisticated tests for the response to
treatment, for the state of the immune system, and for HIV's
resistance to various drugs. They describe these drugs'
unanticipated side effects, among which are changes in peoples'
appearances and increases in the lipid levels of their blood. They
offer advice on adhering to the drugs' regimen--a regimen so strict
and demanding that even AIDS doctors, in trials using placebos,
failed it. And they explain the medical strategies by which the
levels of HIV can be pushed down to an undetectable level and made
to stay there.
The authors emphasize the importance of receiving this good news
cautiously. Though improvements in the drugs have made them easier
to take, they still cost between $10,000 and $12,000 per year, and
no oneknows whether HIV will develop resistance to them. New
stresses accompany this uncertainty, and new perspectives accompany
this new world. This latest Guide to Living with HIV Infection
offers valuable advice both to those for whom treatment works and
to those for whom it doesn't--all focused on remaining well as long
as possible. The book continues to be the most complete source of
medical, emotional, social, financial, and legal advice for people
with HIV infection and for their families and friends.
New to this edition: ? Using the CD4 cell count and viral load
tests to monitor response to treatment, to assess prognosis, and to
indicate the state of the immune system ? New tests of HIV's
resistance to the various drugs against HIV
? Advice on when to start treatment
? Strategy for achieving "no detectable virus"
? Tricks for adhering to the strict regimen required by the
anti-HIV drugs
? New information on the unanticipated side effects of the
anti-HIV drugs
? Advice to women with HIV infection who become pregnant ? New
information on the risks of transmitting HIV
? Changes in emotional perspective resulting from living with
HIV infection
? New guidelines for choosing a physician
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