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Drug Discovery and Design Using Natural Products (1st ed. 2023)
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Drug Discovery and Design Using Natural Products (1st ed. 2023)
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Historically, natural products have great relevance for the
development of new drugs. Natural molecules, in addition to
directly providing new compounds with different therapeutic
functions have provided scaffolds and a great diversity of
structures that serve as inspiration for the design and discovery
of new drugs. The great structural complexity and the significant
number of natural compounds that can be obtained and their
advantages also present some historical problems that need to be
overcome. Issues such as difficulty in isolation, difficulty in
synthesizing compounds found in nature in the laboratory, screening
to evaluate the biological properties of these compounds, and
structural optimization to enhance the pharmacological properties
of biomolecules; are some of the main difficulties encountered in
research with natural products and in the design/discovery of new
medicines. Therefore, this book addresses the great scientific
advances that provide practical solutions to using natural products
to develop new drugs. We address topics related to the genesis of
research projects that use natural products to design new drugs. We
address the discovery of new species, initial processes for
identification and extraction of compounds, isolation and
identification of these structures, techniques, and advances in
vitro and in vivo methods that support the discovery of new natural
drugs, synthesis of new compounds from natural molecules, in silico
optimization processes of potentially promising compounds.
General
Imprint: |
Springer International Publishing AG
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Country of origin: |
Switzerland |
Release date: |
September 2023 |
Editors: |
Jorddy Neves Cruz
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Dimensions: |
235 x 155mm (L x W) |
Pages: |
672 |
Edition: |
1st ed. 2023 |
ISBN-13: |
978-3-03-135204-1 |
Categories: |
Books
Promotions
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LSN: |
3-03-135204-1 |
Barcode: |
9783031352041 |
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