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Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Neurosciences
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The Development of the Rat Spinal Cord (Paperback)
Loot Price: R2,858
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The Development of the Rat Spinal Cord (Paperback)
Series: Advances in Anatomy, Embryology and Cell Biology, 85
Expected to ship within 10 - 15 working days
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The study of the development of the spinal cord has a relatively
long history. The spinal cord was singled out as a favorable site
when cytological techniques were first applied to the study of the
embryonic development of the nervous system. Bidder and Kupffer
(1857), using the new procedure of hardening nerve tissue with
chromic acid (Hannover 1844), made an investigation of spinal cord
development in fetal sheep. They reported that the cellular central
mass of the spinal cord develops before its fibrous envelope,
deducing from this that the fibers of the white matter of the
embryonic spinal cord were outgrowths of cells in the gray matter.
Bidder and Kupffer also noted that in the spinal ganglia fibers
grew out from cells in both directions, peripherally and centrally.
Their report was one of the earliest ontogenetic lines of evidence
in support of the later-formulated neuron doctrine (Waldeyer 1891).
The spinal cord re mained a favorite topic of morphogenetic studies
of the nervous system through out the last quarter of the
nineteenth century, with seminal contributions made by His (1886,
1889), von Lenhossek (1889), Retzius (1898), and Ramon y Cajal
(1960). Indeed, the preoccupation with the spinal cord in the early
investigations of neural development had a lasting, and to some
extent regrettable, influence on ideas about the ontogeny of the
brain and on the terminology adopted by anatomists."
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