In the post-genome era, questions concerning gene products,
enzymes, and metabolism are returning to the forefront of life
science research. Genetic information on its own does not fully
account for an enzyme's kinetic and regulatory properties or for
the behavior of the enzymes within its particular cellular milieu.
Unanswered questions about the regulation, integration, and
adaptation of metabolism have led to a resurgence of interest in
protein, enzymological, and metabolic research for understanding
biological processes.
Functional Metabolism: Regulation and Adaptation provides a
comprehensive survey of metabolism. It includes an in-depth
examination of the regulation of carbohydrates, lipids, and amino
acids, and approaches to the study of enzyme regulation, signal
transduction, and control of transcription and translation. The
contributors-an internationally recognized group of
researchers-also cover:
- The metabolic basis of diabetes, obesity, and blood
disorders
- Oxidative stress and antioxidant defenses in health and
disease
- Novel perspectives on biochemical adaptation to environmental
stress
- Application of metabolic knowledge to developments in organ
preservation and understanding the origin of life
From the basics of metabolic regulation and adaptation to the
latest relevant advances in the genetic, proteomic, and enzymatic
basis of how cells regulate their functions, Functional Metabolism:
Regulation and Adaptation offers the most exhaustive treatment of
the subject currently available. It is an essential text for
students and practitioners in biochemistry, cell and molecular
biology, and biomedicine.
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