Depression is one of the most prevalent and life-threatening forms
of mental illnesses associated with significant disability and
mortality. Stress can be considered as a major contribution for the
development of depressive disorder due to dysregulation of
HPA-axis. Although there are multiple pathways that are involved in
the pathogenesis of depression, the current antidepressants mainly
target monoaminergic pathway. However, therapeutic potential of
other pathways is still under investigation. Drugs targeting nitric
oxide, cytokines and kynurenine acid pathway might be the drugs of
choice in near future. Alzheimer's disease is a neurodegenerative
disorder with progressive dementia. Although basic research in
Alzheimer's disease has made remarkable progress in past 2 decades,
currently available drugs are able to improve cognitive symptoms
temporarily, and no treatment can reverse, stop, or even slow this
inexorable neurodegenerative process. This book dwells on the
recently unravelled pathogenetic hypothesis and therapeutics of
mental depression and Alzheimer's disease.
General
Imprint: |
Lap Lambert Academic Publishing
|
Country of origin: |
Germany |
Release date: |
June 2011 |
First published: |
June 2011 |
Authors: |
Kanwaljit Chopra
|
Dimensions: |
229 x 152 x 5mm (L x W x T) |
Format: |
Paperback - Trade
|
Pages: |
88 |
ISBN-13: |
978-3-8443-1518-9 |
Categories: |
Books >
Medicine >
Other branches of medicine >
Pharmacology >
General
|
LSN: |
3-8443-1518-7 |
Barcode: |
9783844315189 |
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