Biochemistry and Molecular Genetics of Cancer Metastasis - Proceedings of the Symposium on Biochemistry and Molecular Genetics of Cancer Metastasis Bethesda, Maryland - March 18-20, 1985 (Paperback, Softcover reprint of the original 1st ed. 1986)

The success rate for treatment of primary neoplasms has improved sig nificantly due to improved surgical, radiotherapy, and chemotherapy methods, and by supportive patient care. In contrast, the treatment of cancer metastases, the cause of most cancer deaths, has not been very successful. Approximately 50% or more of patients with primary malignant neoplasms already have established metastases. Consequently, the most important problem in cancer treatment is the destruction or prevention of metastases. Metastases research has obvious clinical importance. Yet it has only been recently that investigators have attempted to study the mechanisms in volved in this process. This is in part due to the complexity of metastases formation. A metastatic colony is the result of a complicated series of steps involving mUltiple tumor host interactions. It is expected that multiple biochemical factors and gene products derived both from the host and the tumor cell may be required for the metastasizing tumor cell to invade, survive host defenses, travel in the circulation, arrest and adhere in the target organ, invade out, and grow as a metastatic colony. Some of these factors have recently been identified by investigators who have focused on individual steps in the metastatic process and have employed new technologies in immunology, biochemistry and molecular biology. The purpose of this volume is to capture some of the excitement in the field of metastases based on such new discoveries.

General

Imprint:	Springer-Verlag New York
Country of origin:	United States
Series:	Developments in Oncology, 41
Release date:	November 2011
First published:	1986
Editors:	Karoly Lapis • L.A. Liotta • A.S. Rabson
Dimensions:	235 x 155 x 19mm (L x W x T)
Format:	Paperback
Pages:	334
Edition:	Softcover reprint of the original 1st ed. 1986
ISBN-13:	978-1-4612-9416-0
Categories:	Books > Science & Mathematics > Biology, life sciences > Biochemistry > General Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General
LSN:	1-4612-9416-9
Barcode:	9781461294160

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