The complement system plays a major role in the host's defence
against infections and in immune complex diseases. Although it is
known to consist of a number of serum and membrane proteins that
interact through a cascade, there is still a poor understanding of
the exact nature of the components and their complex interaction.
Many of the biological consequences of complement activation also
await elucidation. This fully revised edition of "Complement in
Health and Disease" provides an up-to-date account of how the
system works and its effects on the host. Key topics covered
include the history, phylogeny and evolution of the system;
genetics and biochemistry; deficiency states and infection; immune
complex diseases; complement and angioedema; anaphylatoxins; and
diseases of the nervous system. The book is valuable both for those
wanting an introduction to this complex area of immunology as well
as those requiring a more detailed update on developments in
specific topics.
General
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