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Antipyretic Activity of Medicinal Plants of Cholistan Desert Pakistan (Paperback)
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Antipyretic Activity of Medicinal Plants of Cholistan Desert Pakistan (Paperback)
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Antipyretic activity of ethanol extracts of Echinops echinatus,
Alhagi maurorum, Fagonia cretica, Cymbopogon jwarancusa and Panicum
turgidum form Cholistan desert, Pakistan was determined. Plant
extracts were prepared by soaking air dried and milled plant
material in ethanol for one week, followed by filtration and
evaporation at 35oC. Treatment does with concentrations of 250, 500
and 750 mg/kg of plant extracts were prepared. Fever was produced
in rabbits, weighting 1000-1200 grams by injecting Escherichia coli
suspension at a concentration of 0.01 ml/kg of body weight. The
ethanol extracts of Fagonia cretica, at the dose of 500 mg/kg and
Pancium turgidum, at the dose of 500 and 750 mg/kg showed
significant antipyretic activity as compared to positive and
negative control. The extracts of Cymbopogon jwarancusa, Alhagi
maurorum and Echinops chinatus showed antipyretic activity but less
than positive control. These results showed that ethanol extracts
of Fagonia cretica and Panicum turgidum are more effective in
lowering temperature as compared to Echinops echinatus, Alhagi
maurorum and Cymbopogon jwarancusa.
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