Providing a comprehensive and critical review of the basic science
and clinical aspects of the drug, this book covers the history and
development of the drug and its current patterns of use and
examines its basic pharmaceutical attributes and medicinal
chemistry. The author discusses the properties of various
formulations and discusses the pharmacokinetics of ibuprofen in
animals and humans--highlighting the factors affecting absorption,
distribution, metabolism, and elimination. Topics include: the
clinical pharmacology and toxicology and the drug's mechanisms of
action in different disease states and conditions, the therapeutic
uses in various acute and inflammatory conditions, and safety
versus efficacy issues and the pharmacoepidemiological data.
General
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