This volume focuses on the use of system genetic methods and the
use of murine models to study the role of gene variants and
environmental factors on human health and disease-what is now often
called personalized or precision health care. The protocols in this
book will help readers analyze genetic causes of heritable
variation across a wide range of systems and traits using rodent
models. The chapters in this book are separated into three sections
that cover: 1) resources for systems genetics; 2) tools for
analysis and integration in systems genetics; and 3) systems
genetics use cases. Written in the highly successful Methods in
Molecular Biology series format, chapters include introductions to
their respective topics, lists of the necessary materials and
tools, step-by-step, readily reproducible protocols, and tips on
troubleshooting and avoiding known pitfalls. Practical and
thorough, Systems Genetics: Methods and Protocols is a valuable
resource for anyone who is interested in this diverse field.
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