Periodontal regeneration is now a major challenge in periodontal
research and practice. It involves the use of regenerative therapy
to restore the defects produced by the defects produced by the
disease process. Bone grafting is known to be one such most
important regenerative procedures.However, the successful
prevention and treatment of periodontitis is contigent upon
effective control of the periodontopathic bacteria residing in the
various ecological niches of the oral cavity. So, Doxycycline have
been incorporated into the allograft to control infection and
facilitate healing during and after periodontal therapy.It has the
ability to concentrate in the GCF at levels, substantially greater
than that in the serum and also binds to the tooth surface to be
slowly released in active form, thereby prolonging therapeutic
effects.It demonstrates anticollagenolytic and antiproteolytic
properties that aid osseous regeneration and also helps in reducing
periodontal disease progression.It has also been shown to initiate
demineralization on the bone surface layer that results in the
release of osteogenic factors such as TGF, IGF& BMP that
triggers bone induction
General
Imprint: |
Lap Lambert Academic Publishing
|
Country of origin: |
Germany |
Release date: |
May 2012 |
First published: |
May 2012 |
Authors: |
Kulmeet Kaur
• Poonam Sikri
|
Dimensions: |
229 x 152 x 7mm (L x W x T) |
Format: |
Paperback - Trade
|
Pages: |
112 |
ISBN-13: |
978-3-659-13856-0 |
Categories: |
Books >
Medicine >
General issues >
General
|
LSN: |
3-659-13856-8 |
Barcode: |
9783659138560 |
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