Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology
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Neoplasms of the Liver (Paperback, Softcover reprint of the original 1st ed. 1987)
Loot Price: R1,708
Discovery Miles 17 080
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Neoplasms of the Liver (Paperback, Softcover reprint of the original 1st ed. 1987)
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Primary liver cancer is a rather unusual malignancy in that the
incidence varies tremendously from one geographical area to
another. While relatively uncom mon in Western countries, it is the
most prevalent malignant neoplasm in Southeast Asia, South Africa,
and many other regions; in all, the countries in which primary
liver cancer is very prevalent account for more than two-thirds of
the world's population. In China alone, approximately 100 000
people die every year from primary liver cancer, mostly
hepatocellular carcinoma. The incidence is rising in some
countries, especially Japan, where it has doubled among males in
the past 15 years or so, a staggering and puzzling trend. Since the
demonstration of an etiological relationship between hepatitis B
virus infection and hepatocellular carcinoma, intensive research
has been con ducted in an effort to elucidate the role of the virus
in hepatocarcinogenesis. Though much progress has been made, a full
understanding of the molecular events leading to malignant
transformation of the hepatocyte will probably require many more
years of rigorous investigation. Chemical carcinogens and several
industrial pollutants may also be involved in the etiopathogenesis
of neoplastic liver disease."
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