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Antibody-Drug Conjugates (Hardcover, 2013 ed.)
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Antibody-Drug Conjugates (Hardcover, 2013 ed.)
Series: Methods in Molecular Biology, 1045
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Antibody-drug conjugates (ADCs) represent a promising therapeutic
approach for cancer patients by combining the antigen-targeting
specificity of monoclonal antibodies (mAbs) with the cytotoxic
potency of chemotherapeutic drugs. In Antibody-Drug Conjugates,
expert researchers provide detailed protocols for many of the key
ADC techniques necessary for working in the field. These chapters
and methodologies are aimed at the key tasks necessary to identify
a suitable target, properly design the mAb, the linker and the
payload, as well as to conjugate them in a reproducible and
scalable fashion. Written in the highly successful Methods in
Molecular Biology (TM) format, these detailed chapters include the
kind of practical implementation advice that guarantees quality
results. Authoritative and timely, Antibody-Drug Conjugates aims to
further drive ADC development and thus help toward improving cancer
treatments of the future.
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