This book covers the latest knowledge in structure, signaling, and
biochemical pharmacology of KOR as well as preclinical research and
clinical applications (including clinical phase studies and
approved for human use) of KOR compounds. It is divided up into the
three parts: Molecular aspects of KOR, Preclinical research on
pharmacology of KOR agonists and antagonists in animals and KOR
agonists and antagonists in clinical use and in past and present
clinical trials. The chapters "Biosensors monitor ligand-selective
effects at kappa opioid receptors" and "The role of dynorphin and
the kappa opioid receptor in schizophrenia and major depressive
disorder: a translational approach" of this book are available open
access under a Creative Commons Attribution 4.0 International
License via link.springer.com.
General
Imprint: |
Springer Nature Switzerland AG
|
Country of origin: |
Switzerland |
Series: |
Handbook of Experimental Pharmacology, 271 |
Release date: |
November 2021 |
First published: |
2022 |
Editors: |
Lee-Yuan Liu-Chen
• Saadet Inan
|
Dimensions: |
235 x 155mm (L x W) |
Format: |
Hardcover
|
Pages: |
577 |
Edition: |
1st ed. 2022 |
ISBN-13: |
978-3-03-089073-5 |
Categories: |
Books >
Medicine >
Other branches of medicine >
Pharmacology >
General
|
LSN: |
3-03-089073-2 |
Barcode: |
9783030890735 |
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