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Natural Products - Drug Discovery and Therapeutic Medicine (Paperback, Softcover reprint of hardcover 1st ed. 2005)
Loot Price: R4,977
Discovery Miles 49 770
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Natural Products - Drug Discovery and Therapeutic Medicine (Paperback, Softcover reprint of hardcover 1st ed. 2005)
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A fresh examination of the past successes of natural products as
medicines and their new future from both conventional and new
technologies. High-performance liquid chromatography profiling,
combinatorial synthesis, genomics, proteomics, DNA shuffling,
bioinformatics, and genetic manipulation all now make it possible
to rapidly evaluate the activities of extracts as well as purified
components derived from microbes, plants, and marine organisms. The
authors apply these methods to new natural product drug
discoveries, to microbial diversity, to specific groups of products
(Chinese herbal drugs, antitumor drugs from microbes and plants,
terpenoids, and arsenic compounds), and to specific sources (the
sea, rainforest, and endophytes). These new opportunities show how
research and development trends in the pharmaceutical industry can
advance to include both synthetic compounds and natural products,
and how this paradigm shift can be more productive and efficacious.
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