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Arenaviruses II - The Molecular Pathogenesis of Arenavirus Infections (Paperback, Softcover reprint of the original 1st ed. 2002)
Loot Price: R1,539
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Arenaviruses II - The Molecular Pathogenesis of Arenavirus Infections (Paperback, Softcover reprint of the original 1st ed. 2002)
Series: Current Topics in Microbiology and Immunology, 263
Expected to ship within 10 - 15 working days
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Viruses are studied either because they cause significant human,
animal or plant disease or because they are useful materials for
probing basic phenomena in biology, chemistry, genetics and/or
molecular biology. Arenaviruses are unusually interesting in that
they occupy both categories. Arenaviruses cause several human
diseases known primarily as the hemorrhagic fevers occurring in
South and Latin America (Bolivia: Machupo, Argentine, Junin virus,
and Brazil: Sabia virus) and in Africa (Lassa fever virus). Because
such viruses produce profound disabilities and often kill the
persons they infect, they are a source of health concern and
economic hardship in the countries where they are prevalent.
Further, they provide new problems for healthcare persons owing to
the narrowing of the world as visitors from many countries travel
increasingly to and from endemic areas and may incubate the
infectious agent taking it from an endemic area into an area where
the virus is not expected. Such cases are now being re corded with
increasing frequency. In addition to these hemor rhagic fever
viruses, the arenavirus lymphocytic choriomeningitis virus (LCMV)
can infect humans worldwide, although the illness is most often
less disabling and severe than those elicited by the other
arenaviruses. Yet, LCMV is of greater concern to non
arenavirologists and experimentalists using tissue culture or ani
mals, etc. , because normal-appearing cultured cells or tissues
from animals used for research may be persistently infected with
LCMV without manifesting clinical disease or cytopathology and may
transmit that infection to laboratory workers.
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