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Contrast-Enhanced Ultrasound in Clinical Practice - Liver, Prostate, Pancreas, Kidney and Lymph Nodes (Paperback, 2005 ed.)
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Discovery Miles 29 570
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Contrast-Enhanced Ultrasound in Clinical Practice - Liver, Prostate, Pancreas, Kidney and Lymph Nodes (Paperback, 2005 ed.)
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The value of ultrasound contrast agents (USCA) in clinical practice
depends on the pharmacokinetics, the signal processing, and the
contrast-specific imaging modalities. USCA are exogenous non-toxic
substances smaller than red blood cells, which after intravenous
administration must be stable enough to pass through the pulmonary
capillary bed and enter the blood pool producing the necessary
contrast enhancement for the duration of the examination. Recently,
second-generation agents, such as SonoVue (Bracco Imaging SpA,
Milan, Italy), have been introduced into the market. These agents,
taking advantage of the stability of their microbubbles, withstand
the acoustic pressure of insonation much better than previous USCA,
resulting in an increased half-life of the agent and thus in a
prolonged diagnostic window. These agents are blood pool agents
that remain in the intravascular compartment and do not leak into
the organ tissue. Therefore, they are used to - crease the Doppler
signal amplitude during their dynamic vascular phase. Concomitant
with the improvement of contrast agents, d- ferent
contrast-specific imaging modalities have been developed which,
used in combination with USCA and a low mechanical - dex (MI),
allow continuous real-time grey-scale imaging. These - cent
technical improvements have opened new possibilities in the use of
USCA in a variety of indications, as shown in the contributions
contained in this book. In the following chapters, some of the most
distinguished users of second-generation USCA will share their
knowledge and experience. The first contributor is Dr. Thomas
Albrecht, Department of - diology, University Hospital of Be
General
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