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Downstream Processing of Natural Products - A Practical Hdbk (Hardcover)
Loot Price: R12,619
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Downstream Processing of Natural Products - A Practical Hdbk (Hardcover)
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Natural Products, broadly defined as high value chemical entities
derived from plants or microbial sources, have been known and
exploited for many years. In recent years, as the need for higher
potency and predictability of such products has increased, more
sophisticated concentration and isolation procedures have been
developed. With the passage of time, such procedures have been
rationalized in terms of scientific principles but, in general,
theory has followed behind practice, leading at any given time to
an absence from the literature of methods which are truly state of
the art. Downstream Processing of Natural Products: A Practical
Handbook is a highly practical manual which addresses this issue,
and guides researchers and industrial workers through the many
potential pitfalls of natural product isolation. The contributors
to this volume, all of whom have wide practical experience in this
field, present state--of--the--art techniques and observations. The
three main stages of natural product purification are covered,
namely product release, capture, and purification, and both
proteins and secondary metabolites are covered. There is special
mention of the requirements of the regulatory authorities with
respect to Good Manufacturing Practice, and practical guidance is
given on scale--up procedures and process scale instrumentation.
Downstream Processing of Natural Products: A Practical Handbook
will provide essential practical guidance to all those involved in
natural product isolation. This includes academic and industrial
researchers, postgraduate students and technicians working in the
biotechnology field.
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