Chronic oxidative stress is associated with the aging process and
often leads to the development of disorders such as cancer and
arterial disease. Cardiovascular conditions in which oxidation
damage has been strongly implicated include atherosclerosis,
myocardial ischemia and reperfusion, coronary restenosis, diabetes
mellitus, and congestive heart failure.
Antioxidants and Cardiovascular Disease, Second Edition covers
three major topics: 1) the first seven chapters review the
oxidative modifcation hypothesis and its close relationship to
lipid metabolism and to the pathogenesis of atherosclerosis; 2) the
next four chapters describe the different compounds, nutrients and
supplements with antioxidant properties and their mechanisms of
action; 3) and finallly, the last ten chapters discuss the
potential benefits of antioxidants in overall cardiovascular
prevention, including hypertension, diabetes mellitus,
dyslipidemias, and in the treatment and prevention of specific
conditions such as chronic coronary artery disease, restenosis
after percutaneous coronary intervention, and chronic heart
failure.
Antioxidants and Cardiovascular Disease, Second Edition is
written by recognized experts in the fields of atherosclerosis,
heart failure and antioxidants. It should be of interest to medical
students and fellows, researchers, and practicing physicians.
There has been rapid progress in our knowledge in this field
during the last two to three years. Thus the current reedition
appears timely. For instance, this second edition captures several
recently reported and published clinical trials as welll as new
information on diabetic and hypertensive cardiovascular
disease.
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