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Neurofibromatosis Type 1 - Molecular and Cellular Biology (Hardcover, 2012 ed.) Loot Price: R5,736
Discovery Miles 57 360
Neurofibromatosis Type 1 - Molecular and Cellular Biology (Hardcover, 2012 ed.): Meena Upadhyaya, David N. Cooper

Neurofibromatosis Type 1 - Molecular and Cellular Biology (Hardcover, 2012 ed.)

Meena Upadhyaya, David N. Cooper

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Loot Price R5,736 Discovery Miles 57 360 | Repayment Terms: R538 pm x 12*

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Neurofibromatosis type 1 (NF1), caused by mutational inactivation of the "NF1" tumour suppressor gene, is one of the most common dominantly inherited human disorders, affecting 1 in 3000 individuals worldwide. This book presents in concise fashion, but as comprehensively as possible, our current state of knowledge on the molecular genetics, molecular biology and cellular biology of this tumour predisposition syndrome.

Written by internationally recognized experts in the field, the 44 chapters that constitute this edited volume provide the reader with a broad overview of the clinical features of the disease, the structure and expression of the "NF1" gene, its germ line and somatic mutational spectra and genotype-phenotype relationships, the structure and function of its protein product (neurofibromin), NF1 modifying loci, the molecular pathology of NF1-associated tumours, animal models of the disease, psycho-social aspects and future prospects for therapeutic treatment.

General

Imprint: Springer-Verlag
Country of origin: Germany
Release date: 2013
First published: 2012
Editors: Meena Upadhyaya • David N. Cooper
Dimensions: 235 x 155 x 43mm (L x W x T)
Format: Hardcover
Pages: 717
Edition: 2012 ed.
ISBN-13: 978-3-642-32863-3
Categories: Books > Medicine > Pre-clinical medicine: basic sciences > Medical genetics
Books > Medicine > Clinical & internal medicine > Neurology & clinical neurophysiology
Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General
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LSN: 3-642-32863-6
Barcode: 9783642328633

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