Human Ageing: A Unique Experience explores the biology of human
ageing focusing on the individual. The book begins with the
premature ageing disorder Hutchinson-Gilford Progeria syndrome and
spins a web of interconnected biological domains involving lamins,
telomeres, alternative splicing, genetics, epigenetics, and
molecular clocks. The profound influence of culture is explored
since cultural inheritance and genetic inheritance are the two
intertwined processes driving human evolution. An empirical
framework is developed to describe human ageing at the individual
level and the implications of this framework on the whole concept
of diseases are discussed.
General
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