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Retinitis Pigmentosa - Causes, Diagnosis & Treatment (Paperback, New)
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Retinitis Pigmentosa - Causes, Diagnosis & Treatment (Paperback, New)
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Retinis Pigmentosa (RP) includes a group of progressive hereditary
retinal diseases involving degeneration of rod and cone
photoreceptors, predominantly the former, and is one of the leading
causes of hereditary blindness in the developed world. Clinical
symptoms include nyctalopia, progressive visual field loss, and
deterioration in visual acuity in adolescence. It affects one in
3000-5000 individuals and can be caused by mutations in more than
40 genes. In addition, Retinitis Pigmentosa may exist either alone
(nonsyndromic) or as part of a neurological or systemic disorder,
such as Usher's syndrome and Infantile Refsum's disease. There are
few effective clinical treatments for retinitis pigmentosa which
affects an estimated 1.5 million individuals world-wide. However,
understanding the histopathologic changes occurring in RP is
critical to understanding the rationale for current therapies, as
well as to develop future therapies. This book highlights the most
recent research done in the field.
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