|
Books > Science & Mathematics > Biology, life sciences > Molecular biology
|
Buy Now
Target Discovery and Validation Reviews and Protocols - Emerging Strategies for Targets and Biomarker Discovery, Volume 1 (Hardcover, 2007 ed.)
Loot Price: R4,413
Discovery Miles 44 130
|
|
|
Target Discovery and Validation Reviews and Protocols - Emerging Strategies for Targets and Biomarker Discovery, Volume 1 (Hardcover, 2007 ed.)
Series: Methods in Molecular Biology, 360
Expected to ship within 10 - 15 working days
|
Target Discovery and Validation: Reviews and Protocols, Volumes 1
and 2 review the most progressive and current methods for drug
target discovery and validation. These volumes explore how recent
improvement in understanding the molecular mechanisms of human
pathology is impacting drug target discovery in the laboratory and
in real therapeutics, specifically for cancers and autoimmune
disorders.
Volume 1 focuses on novel and innovative techniques, and presents
the most up-to-date protocols available for maximizing the
likelihood of achieving target-selective inhibition in vivo while
minimizing side effects. The profound impact of genomics,
proteomics and bioinformatics on target discovery is explored, and
specific attention is given to the role of transgenic and knockout
animals in functional genomics and target validation. Cancer
researchers will find tremendous value in the molecular
classification of breast cancers and the review of protocols for
tumor antigens and cancer vaccines. The methods and protocols
collected here, all reviewed by leading scientists and clinicians,
present the practical details necessary for translating the
enormous discovery potential of the genome into real therapeutic
products.
Volume 2 collects all the practical details required for efficient
translation of discovered targets into real pharmaceutical drugs.
Specific targets in cancers and autoimmunity are described and the
potential of using siRNA's, antisense oligonucleotides and RNA
aptimers in patients is reviewed. This volume explores the
tremendous impact of the application of genotyping and gene
expression profiling on the future of healthcare, and presents
cutting-edge protocols to aid inbringing agents against specific
targets closer to application in the clinic.
Collectively, these volumes provide a thorough review of the most
cutting-edge methods available for each step in drug target
identification, validation, and clinical application. For
researchers, an understanding of available methods aids in the
creation of innovative experiments in the laboratory, and the
successful translation of target discovery to real therapeutics.
General
Is the information for this product incomplete, wrong or inappropriate?
Let us know about it.
Does this product have an incorrect or missing image?
Send us a new image.
Is this product missing categories?
Add more categories.
Review This Product
No reviews yet - be the first to create one!
|
You might also like..
|
Welcome to Loot.co.za!
Sign in / Register |Wishlists & Gift Vouchers |Help | Advanced search
