Books > Medicine > Pre-clinical medicine: basic sciences > Human reproduction, growth & development > Reproductive medicine
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Intracytoplasmic Sperm Injection (ICSI) - Clinical Considerations, Outcomes and Potential Health Effects (Hardcover)
Loot Price: R3,216
Discovery Miles 32 160
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Intracytoplasmic Sperm Injection (ICSI) - Clinical Considerations, Outcomes and Potential Health Effects (Hardcover)
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This book provides comprehensive information on Intracytoplasmic
Sperm Injection (ICSI), its clinical considerations, outcomes and
potential health effects. Male and female infertility is increasing
all over the world. The basic techniques of assisted reproduction
like ovulation control and intrauterine insemination are
ineffective if the sperm quality or number is inadequate. The
advanced fertilization techniques are in-vitro fertilization (IVF)
and ICSI. In 15% cases of infertility, IVF results in total failed
fertilization; therefore, ICSI must be used. Some clinics
exclusively use ICSI for all infertility patients due to its
reliability of fertilization outcome or to avoid total
fertilization failure. ICSI was first used in humans in 1992. Since
then, tremendous advances have been made in assisted reproductive
technology. ICSI has enabled even those men who have rare sperm in
their testes to father a biological child. If no sperm are observed
in the ejaculate, in almost all cases, they can be recovered from
the testicles. Such retrieved sperm can only be used by ICSI.
Therefore, its understanding is essential not only for medical
staff but also for patients suffering from infertility. This book
is highly recommended for patients suffering from infertility or
currently undergoing infertility treatment. It explains the factors
affecting ICSI success rate. In ICSI, the embryologist picks a
sperm for injection to fertilize oocytes whereas in intrauterine
insemination and IVF, one sperm penetrates naturally. This manual
selection of sperm has raised concerns especially in those patients
suffering from severe male factor infertility. The nature of sperm
defects varies and could be congenital, acquired or genetic.
Children born through ICSI are, therefore, considered at higher
risk of carrying the defect. Many investigations have been carried
out to compare incidence of the defects between children conceived
naturally and conceived through ICSI. Additional technologies have
been developed to ensure the birth of a normal child. These include
pre-implantation genetic testing and non-invasive prenatal testing.
This book addresses these concerns and explains the health effects
on children born through ICSI. This book is very useful for medical
students, andrologists, embryologists, nurses or anyone else
interested in learning basic or advanced knowledge of assisted
reproductive technology, especially ICSI. The authors of the
chapters of this book are highly experienced and from different
parts of the world. Many of them are directing very busy ART
laboratories at leading infertility clinics in the United States of
America, Canada and the Middle East.
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