Oligonucleotide-Based Drugs and Therapeutics - Preclinical and Clinical Considerations for Development (Hardcover)

Antisense-based drugs are part of a growing number of pharmaceutical and biotech programs to treat diseases including cancer, diabetes, and ALS. Reviewing fundamentals and offering guidelines for drug discovery and development, this book is a practical guide from the safety assessment to clinical experience with antisense oligonucleotides. Examines principles and tools for scientists in both pre-clinical and clinical settings and how to apply them to antisense oligonucleotides Reviews fundamentals and provides guidelines for scientists in drug design and discovery to increase efficiency, assessment, and success of drug candidates Helps readers understand antisense molecules and their targets, biochemistry and toxicity mechanisms, roles in disease, and applications for safety and therapeutics Includes interdisciplinary perspectives, from both academia and research, on a hot topic that combines pharmacology, toxicology, biology, and medicinal chemistry to advance our understanding and application of therapeutics

General

Imprint:	John Wiley & Sons
Country of origin:	United States
Release date:	September 2018
First published:	2018
Authors:	N Ferrari
Dimensions:	238 x 160 x 37mm (L x W x T)
Format:	Hardcover
Pages:	576
ISBN-13:	978-1-118-53733-6
Categories:	Books > Professional & Technical > Industrial chemistry & manufacturing technologies > Industrial chemistry > Pharmaceutical technology Promotions
LSN:	1-118-53733-5
Barcode:	9781118537336

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