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Determination of Photolytic Degradation of Angenta(R) (Paperback)
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Determination of Photolytic Degradation of Angenta(R) (Paperback)
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The drugs which are photo sensitive should be packed by a kind of
system thus the product cannot be degraded. Now a day, it has been
seen that some pharmaceutical companies do not follow the standard
packaging system and for similar kind of product different types
packaging are being introduced. This is a type of research report
designed to determine the photolytic degradation of an
antipsychotic drug Angenta(r), product of Healthcare
Pharmaceuticals Ltd., Bangladesh, is a combination of contains
flupentixol INN 0.5 mg (as di-hydrochloride) and melitracen INN 10
mg (as di-hydrochloride). By conducting various type of physical,
chemical and instrumental tests were done to determine whether the
product is photo sensitive or not in various conditions (control,
direct sunlight, normal light, 25watt and 40watt light condition).
Some tests include, physical tests (hardness, thickness, weight
variation, friability, color etc.), UV-Spectroscopy. It was
observed that the potency of Angenta(r)was decreased gradually in
various conditions after light exposure and radiation may hamper
the content uniformity of the tab
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