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Implementing and Evaluating Genomic Screening Programs in Health Care Systems - Proceedings of a Workshop (Paperback)
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Implementing and Evaluating Genomic Screening Programs in Health Care Systems - Proceedings of a Workshop (Paperback)
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Genomic applications are being integrated into a broad range of
clinical and research activities at health care systems across the
United States. This trend can be attributed to a variety of
factors, including the declining cost of genome sequencing and the
potential for improving health outcomes and cutting the costs of
care. The goals of these genomics-based programs may be to identify
individuals with clinically actionable variants as a way of
preventing disease, providing diagnoses for patients with rare
diseases, and advancing research on genetic contributions to health
and disease. Of particular interest are genomics- based screening
programs, which will, in this publication, be clinical screening
programs that examine genes or variants in unselected populations
in order to identify individuals who are at an increased risk for a
particular health concern (e.g., diseases, adverse drug outcomes)
and who might benefit from clinical interventions. On November 1,
2017, the National Academies of Sciences, Engineering, and Medicine
hosted a public workshop to explore the challenges and
opportunities associated with integrating genomics-based screening
programs into health care systems. This workshop was developed as a
way to explore the challenges and opportunities associated with
integrating genomics-based programs in health care systems in the
areas of evidence collection, sustainability, data sharing,
infrastructure, and equity of access. This publication summarizes
the presentations and discussions from the workshop. Table of
Contents Front Matter 1 Introduction 2 Evidence Considerations for
Integrating Genomics-Based Programs into Health Care Systems 3
Financial Considerations for Implementing Genomics-Based Screening
Programs 4 Exploring Approaches to Optimize Data Sharing Among
Early Implementers of Genomics-Based Programs 5 Understanding
Participant Needs and Preferences and Improving Diversity and
Equity 6 Improving Health Through the Integration of Genomics-Based
Programs: Potential Next Steps References Appendix A: Workshop
Agenda Appendix B: Speaker Biographies Appendix C: Statement of
Task Appendix D: Registered Attendees
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