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Books > Medicine > Clinical & internal medicine > Endocrinology
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Prolactin (Hardcover, 2001 ed.)
Loot Price: R4,077
Discovery Miles 40 770
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Prolactin (Hardcover, 2001 ed.)
Series: Endocrine Updates, 12
Expected to ship within 18 - 22 working days
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It is an authentic privilege to have the opportunity to assemble
and edit a new volume on "Prolactin," the first in several decades
to be devoted to this fascinating hormone in all its aspects. The
obvious clinical rationale for understanding prolactin (PRL) is the
frequent occurrence of prolactinomas, the most common type of
pituitary tumor. Fortunately, medical management of prolactinomas
can be based on our under standing of the physiology of
hypothalamic control of the lactotroph. Armed with this knowledge,
therapies for proiactinomas are highly successful and well
tolerated. Be cause of the historical and practical importance of
knowledge regarding the hypothala mus-Iactotroph axis, the first
chapters of this volume are dedicated to reviewing the physiology,
development, and cell biology of lactotroph regulation. Chapters
focusing on prolactinomas and related clinical issues follow these.
PRL is the primary hormone that is responsible for "parental care"
in many verte brate species. This reproductive strategy is not
unique to mammals, but it has devel oped through evolution to be
the central distinguishing feature of the mammalian life cycle.
Among the mammals, mice have become the most effective research
species in recent years. This can be traced to the development of a
wide range of methods for manipulating mouse genetics, and thereby
influencing development, physiology and behavior. Mice also provide
a profound illustration of the physiological challenges faced in
maternity. Female mice undergo a post-partum estrous, and often are
both pregnant and lactating simultaneously."
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