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New Organocatalytic Strategies for the Selective Synthesis of Centrally and Axially Chiral Molecules (Hardcover, 1st ed. 2018)
Loot Price: R3,263
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New Organocatalytic Strategies for the Selective Synthesis of Centrally and Axially Chiral Molecules (Hardcover, 1st ed. 2018)
Series: Springer Theses
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This thesis discusses the use of asymmetric organic catalysis for
the direct enantioselective synthesis of complex chiral molecules,
and by addressing the many aspects of both vinylogy and
atropisomerism, it appeals to researchers and scholars interested
in both areas. Organocatalysis is a relatively modern and "hot"
topic in the chemical community; it is constantly expanding and its
use has been extended to interesting areas like vinylogous
reactivity and atropisomerism. Vinylogous systems are very
important for their synthetic applications but also pose a number
of challenges, the most notable of which are their reduced
reactivity and the reduced stereocontrol at these positions. On the
other hand, atropisomeric systems are even more important because
of the huge potential they have as drugs, ligands and catalysts.
Chemists have only recently "recognized" the importance of these
two areas and are focusing their efforts on studying them and the
challenges they pose. This thesis offers an extensive introduction
on the general aspects of chirality and organocatalysis and an
equally extensive experimental section that allow nonexperts to
understand the discussion section and reproduce the experiments.
General
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