Following 50 years of glucocorticoid use in a clinical setting, an
international body of expert scientists and physicians presents the
most expansive survey of glucocorticoid pharmacology to date. This
work traces the history of glucocorticoid biology from the seminal
description of glucocorticoid insufficiency by Thomas Addison in
the mid-19th century, up to current advances in elucidating the
molecular basis of glucocorticoid action. Important discoveries are
presented, as well as milestones in drug development, a survey of
current clinical practice, and prospects for novel
glucocorticoid-based therapeutics. Scientists and clinicians will
appreciate the scope of this work, which is of special interest to
workers in the fields of endocrinology, inflammation and autoimmune
disease.
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