Triglycerides have been shown to be a biochemical predictor of
newborn weight and risk of large for gestational age (LGA) in a few
previous small studies. The objective of this study is to ascertain
whether mid-pregnancy fasting serum triglycerides can predict the
risk of developing LGA and newborn weight in non-diabetic pregnant
mothers.Universal sampling of pregnant mothers attending the
antenatal clinic at the Hospital Universiti Sains Malaysia (HUSM)
and nearby clinics between 24 to 32 weeks gestation was carried
out. Expectant mothers were screened for exclusion criteria
including diabetes, hypertension, pre-eclampsia, fetal anomaly and
multiple gestations. Those who were sure of dates and consented for
the study were enrolled. Modified oral glucose tolerance test
(MOGTT) was performed and fasting serum triglycerides and total
cholesterol were analysed. The subjects were followed up at
delivery when the period of gestation, the birth weight and the sex
of newborn were noted. In NGT subjects, mid-pregnancy high FPG and
high triglycerides value could be used to predict risk of getting
LGA newborn.
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