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Systemic, Cellular & Molecular Mechanisms of Physiological Functions & Their Disorders - Proceedings of I Beritashvili Center for Experimental Biomedicine 2015 (Hardcover)
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Systemic, Cellular & Molecular Mechanisms of Physiological Functions & Their Disorders - Proceedings of I Beritashvili Center for Experimental Biomedicine 2015 (Hardcover)
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This book presents results of current research conducted in the I.
Beritashvili Center of Experimental Biomedicine (former I.
Beritashvili Institute of Physiology, Tbilisi, Georgia) and is
devoted to the experimental investigation of systemic, cellular and
molecular mechanisms of physiological functions and their disorders
in pathology. More precisely, the results of the following studies
are described and discussed: The new, original theory of the fourth
main state of an organisms vitality; memory impairments following
excitotoxic lesions; biologically positive behavioral indices of
the transition state, caused by informational stress and their
pharmacological regulation; functioning of mechanisms responsible
for perception constancy; peculiarities of EEG characteristics in
individuals with attention deficit hyperactivity disorder;
neuroanatomy and neurochemistry of the basic mechanisms for
neocortical and hippocampal arousal; changes in learning ability
and induction of aggressive behavior caused by manganese loading
and ionising radiation; hippocampal activity during learning in
different behavioral paradigms; molecular mechanism of PARP-1
action; significance of the diencephalic GABAergic neurons in
normal and pathological activity of the brain; cellular mechanisms
of antinociceptive tolerance; thermal stability of model globular
protein; kinetic features of transport ATPases; antiseizure drugs
and EEG in epileptic patients; effect of depakin on EEG
epileptiform elements; how six domains form one enzyme; therapeutic
potential of extracellular ubiquitin; effect of toluene chronic
exposure on hippocampal structure; and the mechanisms of local
hyperthermia caused by morphological changes in cerebral tissue.
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