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Books > Medicine > Other branches of medicine > Pharmacology
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An Efficient Pyrimidine Scaffolds Against Bacterial Strains (Paperback)
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Discovery Miles 19 010
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An Efficient Pyrimidine Scaffolds Against Bacterial Strains (Paperback)
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A series of novel 2-(substituted
benzylidene)-7-(4-bromophenyl)-5-(furan-2-yl)-2H-thiazolo
3,2-a]pyrimidin-3(7H)-ones were synthesized by using established
methods and were characterized by IR, 1H NMR and Mass spectroscopy
in order to confirm their formation. These compounds were
synthesized to evaluate their antitubercular, antibacterial and
antifungal potency. Docking studies revealed the importance of
functional groups and its different biological action. They were
found to be potent against Mycobacterium tuberculosis H37Ra strain,
also potent against Gram +ve, Gram -ve and fungal strains
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