Synthesis and Antibactarial Evaluation Novel Triazol Derivatives (Paperback)

Heterocycles bearing a triazole ring residue are reported to show anticancer, anti-inflammatory, analgesic, antifungal, antitubercular, antimicrobial, antiviral, antioxidant, CNS depressant, and plant growth regulatory activity etc. Keeping in view the importance of Triazole from the literature survey I found various triazole derivatives & from that I planned to work the substituted triazole derivatives from m-nitro benzoic acid, which gives various anticipated biological activities. Among the all synthesized compound, compound 6-(2-chloro-phenyl)-3-(4-nitro-phenyl)- 1,2,4]triazolo 3,4-b] 1,3,4]thiadiazole (PLP 105b) with MIC value of (16ug/ml) against gram-positive (B.subtilis) and (16ug/ml) against gram-negative (E.coli, p.aeroginosa)and the compound3,6-bis-(4-nitro-phenyl)- 1,2,4]triazolo 3,4-b] 1,3,4]thiadiazole (PLP 105d) with MIC value of (16ug/ml) against gram-negative (p.aeroginosa) give better antimicrobial activity than other synthesized compound."

General

Imprint:	Lap Lambert Academic Publishing
Country of origin:	United States
Release date:	April 2013
First published:	April 2013
Authors:	Patel Chirag J. • Gali Vidyasagar • Pratik Patel
Dimensions:	229 x 152 x 5mm (L x W x T)
Format:	Paperback - Trade
Pages:	88
ISBN-13:	978-3-659-38697-8
Categories:	Books > Medicine > Other branches of medicine > Pharmacology > General
LSN:	3-659-38697-9
Barcode:	9783659386978

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