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Metabolism of Drugs and Other Xenobiotics (Hardcover)
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Metabolism of Drugs and Other Xenobiotics (Hardcover)
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A practice-oriented desktop reference for medical professionals,
toxicologists and pharmaceutical researchers, this handbook
provides
systematic coverage of the metabolic pathways of all major classes
of xenobiotics in the human body. The first part comprehensively
reviews
the main enzyme systems involved in biotransformation and how they
are orchestrated in the body, while parts two to four cover the
three
main classes of xenobiotics: drugs, natural products, environmental
pollutants. The part on drugs includes more than 300 substances
from
five major therapeutic groups (central nervous system,
cardiovascular system, cancer, infection, and pain) as well as most
drugs of abuse
including nicotine, alcohol and "designer" drugs. Selected,
well-documented case studies from the most important xenobiotics
classes illustrate general principles of metabolism, making this
equally useful for teaching courses on pharmacology, drug
metabolism or molecular
toxicology.
Of particular interest, and unique to this volume is the inclusion
of a wide range of additional xenobiotic compounds, including food
supplements, herbal preparations, and agrochemicals.
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