MicroRNAs as the endogenous mediators of RNA interference have
experienced an unprecedented career in recent years, highlighting
their pathogenic, diagnostic and potential therapeutic relevance.
Beside tissue microRNAs, they are also found in body fluids, most
notably in blood. Significant differences of circulating microRNA
levels have been found in various diseases, making them candidates
for minimally invasive markers of disease, for example tumor
malignancy. The book focuses on the potential diagnostic
applicability of circulating microRNAs in various diseases and
their potential biological significance.
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