Alternative Splicing - Methods and Protocols (1st ed. 2022)

This detailed volume collects commonly used and cutting-edge methods to analyze alternative splicing, a key step in gene regulation. After an introduction of the alternative splicing mechanism and its targeting for therapeutic strategies, the book continues with techniques for analyzing alternative splicing profiles in complex biological systems, visualizing and localizing alternative spliced transcripts with cellular and sub-cellular resolution, probing regulators of alternative splicing, as well as assessing the functional consequences of alternative splicing. Written for the highly successful Methods in Molecular Biology series, chapters include introduction to their respective topics, lists of the necessary materials and reagents, step-by-step, reproducible protocols, and tips on troubleshooting and avoiding known pitfalls.  Authoritative and practical, Alternative Splicing: Methods and Protocols serves as an ideal guide for both RNA aficionados that want to implement novel approaches in their labs and novices undertaking alternative splicing projects.

General

Imprint:	Springer-Verlag New York
Country of origin:	United States
Series:	Methods in Molecular Biology, 2537
Release date:	August 2023
First published:	2022
Editors:	Peter Scheiffele • Oriane Mauger
Dimensions:	254 x 178mm (L x W)
Pages:	354
Edition:	1st ed. 2022
ISBN-13:	978-1-07-162523-1
Categories:	Books
LSN:	1-07-162523-3
Barcode:	9781071625231

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