Books > Medicine > Clinical & internal medicine > Gynaecology & obstetrics
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Trends in Oral Contraception - The Proceedings of a Special Symposium held at the XIth World Congress on Fertility and Sterility, Dublin, June 1983 (Paperback, 1st ed. Softcover of orig. ed. 1983)
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Trends in Oral Contraception - The Proceedings of a Special Symposium held at the XIth World Congress on Fertility and Sterility, Dublin, June 1983 (Paperback, 1st ed. Softcover of orig. ed. 1983)
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After 20 years of oral contraceptive (OC) use, epidemiological data
and scientific research have led to the now accepted evidence that
the most important effect produced by these drugs on humans, other
than the prevention of unwanted pregnancy, is an increase in the
risk of cardiovascular disease. Because the incidence of
cardiovascular disease is also related to disturbances of the
lipoprotein metabolism, it appears to be opportune to analyse the
different aspects of the interaction between female hormones and
lipoprotein (LP) metab- olism. SERUM LIPOPROTEINS: METABOLISM In
the serum, lipids (cholesterol (C), triglycerides (TG), and
phospho- lipids) are associated with peptides called apoproteins:
apoproteins A-I, A-11, B, C, etc. The chylomicrons and the very low
density lipoproteins (VLDL) are rich in TG and contain the Apo
B-48; the low density lipoproteins (LDL) are rich inC and contain
the Apo B- 100; and the high density lipoproteins (HDL) are rich in
proteins (Apo A-I, Apo A-Il) and phospholipids.
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