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Books > Medicine > Clinical & internal medicine > Gynaecology & obstetrics
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Polycystic Ovary Syndrome (Paperback, Softcover reprint of the original 1st ed. 1996)
Loot Price: R2,678
Discovery Miles 26 780
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Polycystic Ovary Syndrome (Paperback, Softcover reprint of the original 1st ed. 1996)
Series: Serono Symposia USA
Expected to ship within 10 - 15 working days
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The term polycystic ovary syndrome (peOS) is meant to describe a
clinical endocrinopathy characterized by menstrual irregularity and
evidence of hyperandrogenism. While recognized since the 1800s, a
clinical composite was not constructed until 1935 when Stein and
Leventhal reported their findings of seven women with infertility,
menstrual dysfunction, hirsutism, and enlarged ovaries. Notably,
the ovaries contained numerous multiple cysts and the ovarian
capsule was thickened. At the time, this preciseness of definition
was sufficient to entitle the entity Stein-Leventhal syndrome.
Subsequently, over the intervening years as investigators attempted
to un ravel the pathophysiology and genesis of this disorder and
the number of reported studies increased, there ensued a gradual
and distinct terminologic conversion to polycystic ovary syndrome,
which, whether intentional or not, connoted a less well-defined
condition. Perhaps this is appropriately so, given the seemingly
broadening spectrum of clinical presentations and the continuing
debate over what constitutes peos. The expansive new knowledge
about peos was discussed to a significant degree at an
international symposium organized by Serono Symposia USA and held
in Boston in the late spring of 1995. Ovarian physiology, including
the fate of the follicular unit, was a central focus with several
presentations on the genesis, growth, and death of ovarian cellular
components. A discus sion of the regulation of ovarian cell
function was also highlighted and comprised a major portion of the
program."
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