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Placental Vascularization and Blood Flow - Basic Research and Clinical Applications (Paperback, Softcover reprint of the original 1st ed. 1988)
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Placental Vascularization and Blood Flow - Basic Research and Clinical Applications (Paperback, Softcover reprint of the original 1st ed. 1988)
Series: Trophoblast Research, 3
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The optimal function of the placenta and thus fetal well being
largely depends upon the integrity of both the fetal and maternal
circulations of the placenta. Intense basic research concerned with
placental vascularization and blood flow has been performed for the
past 30 years, beginning with the classical morphological
descriptions of the placental vessels by Boe (1953) and Arts
(1961), as well as with the radioangiographic studies of maternal
placental circulation in the human by Borell (1958) and in the
rhesus monkey by Ramsey (1962). The scientific framework presented
by these investigators has been filled and completed by numerous
investigators, leading to more morphological details, functional
considerations, and pathological understanding. For an extended
period of time, this research has been of primarily academic
interest by increasing our insights into one important system of
the placenta, yet having nearly no practical importance. Recently,
this situation has changed dramatically: in vitro studies of the
isolated, dually perfused human placenta and in vivo studies of
placental circulation for diagnostic purposes have raised an
enormous interest in basic research data. New methods like Doppler
Ultrasound and NMR became available. These technics have enabled
the obstetrician to study fetal and placental hemodynamics in vivo.
Meanwhile, such methods are becoming incorporated into the daily
obstetrical routine, to some degree without an adequate background
knowledge of placental vascularization and blood flow, since such
experience is currently available to only a small group of experts.
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