Aldol Reactions provides a comprehensive up-to-date overview of
aldol reactions including application of different metal enolates;
catalytic aldol additions catalyzed by different Lewis acids and
Lewis bases; enantioselective direct aldol additions; antibodies
and enzyme catalyzed aldol additions and the recent aggressive
development of organocatalyzed aldol additions.
The power of each method is demonstrated by several applications
in total synthesis of natural products. The pros and cons of these
methodologies with regard to stereoselectivity, regioselectivity
and application in total synthesis of natural products are
discussed. Great importance is set to the diverse possibilities of
the manual of aldol reaction to install required configurations in
complicated natural product synthesis.
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