Most of the pharmaceutical industries, are manufacturing multiple
drug formulation to meet the market demand. This drug combination
has more advantages and efficiency as compared single drug
components. Quantitative analysis of multicomponent formulations
usually requires a prior extraction of drugs from the excipients or
elaborate separation procedure for multiple drug themselves, hence
making them tedious and time consuming. There is likely to be loss
of accuracy and precision due to extraction and separation. The
simultaneous analysis procedures avoid these time consuming
extraction and separation, and are economical in the sense that use
of expensive reagents is minimized. As a result, a simple, rapid
and economical method for the simultaneous analysis of
multicomponent formulations, which do not require extraction or
separation of the analyte from themselves or from the excipients,
becomes necessary for the pharmaceutical industry. Therefore, in
the proposed project, a successful attempt has been made to develop
simple, precise and accurate methods for the simultaneous analysis
of Drotaverine Hydrochloride and Nimesulide in a two component
tablet formulation.
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