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Natural Products Chemistry - Sources, Separations and Structures (Paperback)
Loot Price: R2,943
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Natural Products Chemistry - Sources, Separations and Structures (Paperback)
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Notoriously cumbersome to isolate and challenging to synthesize,
the path of natural products to viable drugs is an arduous journey.
Yet compounds isolated from nature may possess fascinating
structures, biological profiles and pharmaceutical potential far
greater than anything made by man. Natural Products Chemistry:
Sources, Separations and Structures presents a practical guide to
sourcing, isolating, and discovering new compounds from nature many
of which become pharmaceutical drugs. This book emphasizes the
challenges and advantages of products acquired from nature,
compared to those obtained from combinatorial chemistry. A basic
introduction, the book describes the whole cycle from farm to final
compound, backed up by case studies drawn from industry and
research applications. It broadens the scope of applications and
draws upon examples from various sources. Natural products
chemistry, as taught today, draws its examples mainly from marine
chemistry or plant chemistry; however, there is also a fascinating
and rich world of fermented (microbial and algal) products leading
to complex structures. Thus, the book draws upon examples from the
microbial world and from insects too. Therefore, this is a source
of bioactive metabolites, not traditionally available in academic
settings, more the mainstay of the pharmaceutical industry.
Providing a roadmap of the process of collecting a compound from
nature, isolating the active ingredient, and determining the
chemical structure, this book provides a unique approach to the
world of natural products.
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