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Essential Genes and Genomes - Methods and Protocols (Hardcover, 1st ed. 2022)
Loot Price: R6,192
Discovery Miles 61 920
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Essential Genes and Genomes - Methods and Protocols (Hardcover, 1st ed. 2022)
Series: Methods in Molecular Biology, 2377
Expected to ship within 12 - 17 working days
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This book provides state-of-the-art information on gene
essentiality screenings in a wide variety of organisms, i.e.
screening for protein-coding genes and other genomic elements that
are required by an organism to survive under specific conditions.
With a focus on the two techniques that have revolutionized the
field, the collection begins with chapters employing
CRISPR/Cas9-based approaches followed by Tn-seq-based approaches,
but later chapters also delve into other techniques for exploring
essential genes, such as bioinformatics methods. Written for the
highly successful Methods in Molecular Biology series, chapters
include introductions to their respective topics, lists of the
necessary materials and reagents, step-by-step, readily
reproducible laboratory protocols, and tips on troubleshooting and
avoiding known pitfalls. Comprehensive and authoritative, Essential
Genes and Genomes: Methods and Protocols is an ideal guide for
researchers attempting to strip genetics down to its fundamentals.
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