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Lactate Dehydrogenase (LDH) - Biochemistry, Function and Clinical Significance (Hardcover)
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Lactate Dehydrogenase (LDH) - Biochemistry, Function and Clinical Significance (Hardcover)
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The book entitled "Lactate Dehydrogenase (LDH): Biochemistry,
Functions and Clinical Significance" provides a broad and
authoritative review of the lactate dehydrogenase enzyme, including
its isoforms, catalytic functions, distribution in various tissues,
involvement in cancer cell metabolism and tumorigenesis,
involvement in the plasmodium enzyme, various small molecule
inhibitors of hLDHA and pfLDH, and clinical significance. Recent
research and review articles are included to improve the book's
significance in the area of research, particularly in cancer
treatment, diagnosis, and drug discovery. Although the chapters can
be read independently from one another, the whole book is arranged
in seven chapters for the convenience of the reader. The first
chapter covers the importance of the hot topic, LDH targets, and
the second chapter provides an overview of LDH and its involvement
in cancer cell metabolism. The third chapter provides the various
isoforms of LDH and the basics of catalytic functions of LDHA. All
three chapters can serve as an introduction for those who are new
to the research area of LDH. Chapters four and five deliver an
overview of various small molecules as inhibitors of hLDHA and
pfLDHA, respectively. These two chapters are useful to the
researcher working in the fields of drug design and drug discovery
in the areas of cancer and malaria research. The last two chapters
focus on the importance of LDH as a biomarker, and its importance
in disease diagnosis and prognosis in clinical settings. All of the
chapters discuss the latest research findings that have occurred
over the last few years. Bringing all the information together in
one major reference, the authors systematically reviewed and
summarized these recent research findings, providing an in depth
understanding of the role of LDH and its applications in research
and clinical practice. Readership: Overall, this book is a complete
package for graduates, students, and researchers providing basic
information about LDH, and its importance in research and clinical
settings. This book is helpful to the researcher engaged in the
fields of LDH, drug design and drug discovery, the development of
biomarkers, disease diagnosis, and prognosis, etc.
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