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Invertebrate Historecognition (Paperback, Softcover reprint of the original 1st ed. 1988)
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Invertebrate Historecognition (Paperback, Softcover reprint of the original 1st ed. 1988)
Series: Bodega Marine Laboratory Marine Science Series
Expected to ship within 10 - 15 working days
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Historecognition, broadly defined, spans the processes responsible
for the regulation of the genetic integrity of self in the face of
conspecific (allogeneic) and heterospecific (xenogeneic) nonself.
The existence of precise historecognition systems in the
invertebrates can be traced back to Bancroft's discovery in 1903
of, strain specific regulation of colony fusion in the compound
ascidian Botryllus schlosseri, and Wilson's report in 1907 of
species-specific sponge re-aggregation. Despite this provocative
history, invertebrate historecognition remained largely unexplored
for over half a century, while studies of vertebrate immune systems
prospered. Then, in the 1970's, interest in invertebrate his tore
cognition grew once again, this time cast largely in terms of
understanding the mechanisms and evolutionary history of vertebrate
immunity. From our current understanding of vertebrate immunity and
invertebrate historecognition, three generalizations about their
relationships can be drawn. First, despite substantial knowledge
about the genetics and molecular biology of cell recognition in the
context of vertebrate immunity and to a lesser extent of
invertebrate historecognition, the evolutionary relationships
between invertebrate self/nonself recognition and vertebrate immune
systems remain obscure. Second, although vertebrate allograft
recognition is of dubious functional significance itself (because
intergenotypic cellular contacts are unusual, except during
fertilization and pregnancy), natural allografts occur frequently
as sedentary invertebrates grow and compete for living space. It is
now known that the operation of invertebrate his tore cognition
systems can profoundly affect the outcomes of competitive
interactions by mediating allogeneic aggressive behavior and
somatic fusion."
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