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Pharmacology of G Protein Coupled Receptors, Volume 62 (Hardcover) Loot Price: R7,186
Discovery Miles 71 860
Pharmacology of G Protein Coupled Receptors, Volume 62 (Hardcover): Richard R Neubig

Pharmacology of G Protein Coupled Receptors, Volume 62 (Hardcover)

Richard R Neubig

Series: Advances in Pharmacology

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Loot Price R7,186 Discovery Miles 71 860 | Repayment Terms: R673 pm x 12*

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G protein coupled receptors remain the most important class of therapeutic targets in medicine. In the last 5 years, tremendous advances have been made in our understanding of the structure and mechanism of this critical family of drug targets. The present volume explores the modern experimental and conceptual framework for drug discovery for G protein coupled receptors. It explores advances in structure determination and structure-based drug design as well as new concepts of allosteric modulation, functional selectivity/biased agonism, and pharmacological chaperones. In addition, emerging drug targets such as receptor families for fatty acids, carboxylic acids, lipid mediators, etc. are included. Final chapters cover novel mechanisms of signal regulation through PDZ domains and RGS proteins. This volumewill bring an up-to-date perspective on the G protein coupled receptor field to both academic and industry scientists.

The present volume explores the modern experimental and conceptual framework for drug discovery for G protein coupled receptors It explores advances in structure determination and structure-based drug design as well as new concepts of allosteric modulation, functional selectivity/biased agonism, and pharmacological chaperones This volume will bring an up-to-date perspective on the G protein coupled receptor field to both academic and industry scientists "

General

Imprint: Academic Press Inc
Country of origin: United States
Series: Advances in Pharmacology
Release date: October 2011
First published: October 2011
Volume editors: Richard R Neubig
Dimensions: 229 x 152 x 24mm (L x W x T)
Format: Hardcover
Pages: 408
ISBN-13: 978-0-12-385952-5
Categories: Books > Medicine > Other branches of medicine > Pharmacology > General
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LSN: 0-12-385952-2
Barcode: 9780123859525

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