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Long Noncoding RNAs - Structures and Functions (Hardcover, 2015 ed.)
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Long Noncoding RNAs - Structures and Functions (Hardcover, 2015 ed.)
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This book presents a common principle of actions of long noncoding
RNAs (lncRNAs) from points of view at the atomic, molecular and
cellular levels. At the atomic level, chemical studies of
ribonucleic acids explain the chemical behavior of lncRNAs.
Structural biological analysis of lncRNAs and its binding proteins
also reveal the precise mechanisms of their actions. Molecular
biological approaches lead to insights into molecular mechanisms of
these lncRNA actions. At the cellular or individual level of
analysis, we grasp the biology and medicine of lncRNAs. These three
layers of approaches are thoroughly new and produce novel insights
into functions of lncRNAs in living cells. The book consists of
five parts: 1) Bioinformatics and other methodologies for lncRNAs,
2) Atomic and molecular structures of lncRNAs, 3) Molecular
functions of lncRNAs, 4) Biological actions of lncRNAs, and 5)
Potential outcomes for clinical medicine. These sections connect
well and work synergistically. The book is for researchers whose
specialty is RNA biology and chemistry and also for advanced
students at the graduate and undergraduate levels. Readers can
grasp the leading edge of lncRNA studies in a comprehensive manner
and are inspired to pursue their own particular interests.
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